Biotechnology
Biotechnology is experiencing a rapid acceleration thanks to the advances in omic techniques and computing capacities, which allow us to better understand how we can put nature’s machinery to use for the good of humanity. Biotechnology is a broad discipline in which biological processes, cells or organisms are exploited to develop new technologies, with applications in agri- and aquaculture, food production, industrial processes and medicine.
Because of this wide range of applications, biotechnology is usually color-coded to refer to its four main fields of application. Industrial biotechnology is usually referred to as white biotechnology, while red is reserved for medical applications, green for agriculture-related developments, and blue for processes that encompass the aquatic environment.
The interdisciplinary nature of the IIM-CSIC allows us to collaborate with different industries for the application of biotechnological innovations across the whole color range of biotechnology.
You can read about all our capabilities and associated services below.
Capabilities
- Patent | Myticin peptide and its use in cell regeneration
Authors: Antonio Figueras Huerta, María Gasset Vega, Beatriz Novoa García, Magalí Rey Campos, Ricardo Mallavía Marín, Regla María Medina Gali, Alicia Martínez López
The present invention relates to peptides derived from myticin C and to their therapeutic use, more specifically in cell and/or tissue regeneration. More detailed information can be obtained here.
- Prototype | Morbidostat: Unraveling Antimicrobial Resistance
Morbidostat is a computer-controlled continuous culture device that automatically adjusts drug concentration to maintain constant growth inhibition in microbial cultures. As bacteria acquire mutations that give them resistance against drugs, they are able to tolerate higher drug concentrations and grow faster, thus removing selective pressure, the driving force of evolution. To compensate for this, morbidostat increases drug concentration sufficiently to keep bacteria at their original growth rate, therefore maintaining selective pressure over time. This system allows for data acquisition to model microbial evolution under antimicrobial stress, optimize biocide dosage strategies and develop highly antimicrobial-resistant strains used to test the performance of new biocides, among other applications.
- Patent | Andrographolide derivatives for their use in the treatment of cytokine-related inflammatory diseases
Authors: Eva María Rivero Buceta; Cristian Smerdou Picazo; Pablo Botella Asunción; Antonio Pineda Lucena; Carla María Vidaurre Agut; Beatriz Novoa; Antonio Figueras Huertas; Jose María Benlloch Baviera
Andrographolide derivatives for their use in the treatment of cytokine-related inflammatory diseases . Patent pending publication.
- Patent | Andrographolide derivatives for their use in the treatment of COVID-19 and associated pulmonary fibrosis
Authors: Antonio Pineda Lucena; Carla María Vidaurre Agut; Eva María Rivero Buceta; Jose María Benlloch Baviera; Cristian Smerdou Picazo; Beatriz Novoa; Antonio Figueras Huertas; Pablo Botella Asunción
Andrographolid derivatives for their use in the treatment of COVID-19 and associated pulmonary fibrosis. Patent pending publication.
- Patent | Compounds having anti-inflammatory activity
Authors: Juan Carlos Espin de Gea; Juan Carlos Morales Sánchez; Isabel Medina
Compounds for the treatment of inflammatory processes involved in numerous diseases such as intestinal inflammatory diseases. The invention mainly refers to compounds included within a certain general formula and to the procedure to obtain them. More detailed information can be obtained here.
Active projects
- LIFE REFISH -
<p>Flexible biorefinery to valorise discards and by-products of the European fish and seafood production (REFISH)</p>
Principal investigator:VázquezÁlvarezXosé AntónFunding body:LIFE Environment (Nature & Circular Economy)Funding for IIM-CSIC:357637€Fromto - METDISHFISH -
<p>Terapias metabólicas para el tratamiento de enfermedades infecciosas en peces de cultivo</p>
Principal investigator:NovoaGarcíaBeatrizFunding body:Ayuda cofinanciada por el Fondo Europeo Marítimo y de Pesca y el Ministerio de Agricultura, Pesca y Alimentación.Funding for IIM-CSIC:324175€Fromto - PESCANDO 4.0 -
<p>Plataforma Blockchain e IoT para garantizar la trazabilidad, seguridad, calidad y sostenibilidad en la cadena de valor de los productos pesqueros</p>
Principal investigator:VilasFernándezCarlosFunding body:PROYECTO FINANCIADO POR EL PLAN DE RECUPERACIÓN, TRANSFORMACIÓN Y RESILIENCIA Y LOS FONDOS EUROPEOS NEXT GENERATION EU EN EL MARCO DEL REAL DECRETO 685/2021 DEL 3 DE AGOSTOFunding for IIM-CSIC:145812€Fromto - BIOTRANSFER -
<p>Polymicrobial L. monocytogenes-carrying biofilms as a key on the risk of listeriosis in foods</p>
Principal investigator:LópezCaboMartaFunding body:CSICFunding for IIM-CSIC:28557€Fromto - VALOR -
<p>Valorización integral de los efluentes y residuos de pieles generados en el proceso de producción de gelatinas marinas de alta calidad</p>
Principal investigator:VázquezÁlvarezXosé AntónFunding body:CSICFunding for IIM-CSIC:21600€Fromto - DTWINE2021 -
<p>Digital Twins to optimize energy efficiency and product quality in WINEries</p>
Principal investigator:BalsaCantoEvaFunding body:Proyecto PLEC2021-007827 financiado por MCIN/ AEI /10.13039/501100011033 y por la Unión Europea NextGenerationEU/PRTRFunding for IIM-CSIC:248164€Fromto - SEAFOOD-ID -
<p>ANALYTICAL STRATEGIES BASED ON NON-DESTRUCTIVE METHODS AND METAGENOMICS FOR THE CONTROL OF PRODUCTION METHOD AND GEOGRAPHIC ORIGIN</p>
Principal investigator:GonzálezSoteloCarmenPérezMartínRicardo IsaacFunding body:Proyecto PID2020-118012RB-C21 financiado por MCIN/ AEI /10.13039/501100011033Funding for IIM-CSIC:168000€Fromto - IMANREFIVIR -
<p>IMMUNE ANTIVIRAL RESPONSE OF FISH AGAINST RNA VIRUSES</p>
Principal investigator:NovoaGarcíaBeatrizFunding body:Proyecto PID2020-119532RB-I00 financiado por MCIN/ AEI /10.13039/501100011033Funding for IIM-CSIC:160000€Fromto - Contrato Programa -
<p>AYUDA CONVENIO ENTRE CSIC Y LA AXENCIA GALEGA DE INNOVACIÓN -GAIN- PARA EL DESARROLLO DE PROGRAMAS DE I+D+i EN LOS INSTITUTOS DE INVESTIGACIÓN DEL CSIC EN GALICIA Y EN LOS CENTROS OCEANOGRÁFICOS DEL INSTITUTO ESPAÑOL DE OCEANOGRAFÍA (CSIC-IEO). 2021-2022</p>
Principal investigator:SaboridoReyFranFunding body:Agencia Galega de InnovaciónFunding for IIM-CSIC:521824€Fromto - ISEAS -
<p>Nanopartículas con hidrolizados de colágeno marino: aplicaciones en cosmética</p>
Principal investigator:PérezMartínRicardo IsaacFunding body:CSICFunding for IIM-CSIC:52000€Fromto